Journey

Run the iZO agent pipeline from payer barrier to briefing

Illustrative synthetic dataOptum RWD · Claims · HEORiZO Context Engine · Medical Affairs · KOL Intelligence

Renvora: from payer access barrier to evidence-backed action

Renvora is a fictional once-daily oral therapy for adults with chronic kidney disease associated with type 2 diabetes. Payer restrictions limit access. iZO agents use simulated Optum evidence to find the barriers, size the patient impact, assemble the evidence, and prepare a payer value brief for Value & Access and a compliant briefing for Medical Affairs.

Primary user
Head of Value & Access / HEOR
Owns payer barriers, patient access and the payer value case.
Downstream user
Medical Affairs and MSLs
Receives the same vetted evidence as a compliant scientific briefing.

iZO Context Engine

Entities linked as each agent completes

Optum dataiZO capability
1ProductiZO capability2Payer segmentOptum data3Access barrierOptum data4Patient cohortOptum data5Evidence setOptum data6KOL / MSLiZO capability7BriefingsiZO capability

Agent trace

0 of 6 agents complete

  • Access Barrier AgentOptum Claimsqueued

    Detects step edits, PA and other restrictions from claims access patterns and a payer policy source (source to be confirmed).

  • Patient Impact AgentOptum RWDqueued

    Quantifies label-eligible patients blocked or delayed by access barriers, using Optum claims and EHR data (simulated).

  • Evidence Synthesis AgentOptum HEORqueued

    Assembles clinical and economic evidence from Optum HEOR evidence services, graded by iZO, aligned to payer criteria.

  • KOL Match AgentiZO KOL Intelligencequeued

    Scores and ranks opinion leaders on a transparent fit score.

  • Payer Brief AgentiZO Context Enginequeued

    Drafts a payer value brief for the Value & Access team.

  • MSL Brief AgentiZO Medical Affairsqueued

    Drafts a compliant MSL briefing for Medical Affairs from the same evidence.